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A blog on the latest applications, articles, & research on chromatography solutions in sample preparation, Ion Chromatography (IC),
High Pressure Liquid Chromatography (HPLC), Ion Chromatography-Mass Spectrometry (IC-MS), Gas Chromatography (GC),
Gas Chromatography-Mass Spectrometry (GC-MS and GC-MS/MS), and software (Chromeleon CDS, LIMS, and ProteinCenter).

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How to Use PTV with Backflush on a Gas Chromatograph

  
  
  
  
  
  
Pesticides, environmental contaminants, drugs of abuse, contamination in matrix, PTV backflush

There are a lot of samples (food, environmental for USenvironmental for EU, drugs of abuse, forensic, or any other type) to analyze.  That means there are a lot of samples to extract and run on the Gas Chromatograph.  We would like to spend as little time as possible on the sample preparation.  However, without sample cleanup the potential to contaminate the GC column and potentially the mass spectrometer source, if that is the detector.  The time that is saved in sample prep could be wasted in maintenance.  That is where backflush comes in.  Backflush on the PTV injector provides the means to remove the high boiling point contamination that will contaminate the column, and the rest of the system, that is missed during a fast sample preparation. 

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