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A blog on the latest applications, articles, & research on chromatography solutions in sample preparation, Ion Chromatography (IC),
High Pressure Liquid Chromatography (HPLC), Ion Chromatography-Mass Spectrometry (IC-MS), Gas Chromatography (GC),
Gas Chromatography-Mass Spectrometry (GC-MS and GC-MS/MS), and software (Chromeleon CDS, LIMS, and ProteinCenter).

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A Chemist, a Biologist and a Systems Architect walk into a bar…

biopharma development (2)

... and none of them could understand what the others were saying.

Trust Your LIMS and Leave the Paper Behind in the R&D Lab


With fewer dollars to go around for R&D and increasing production costs, the life sciences industry must root out inefficiencies wherever possible and build in new processes to achieve improved productivity and greater efficiencies across an oftentimes much broader organization, starting with the laboratory. New technologies help accelerate discovery, which adds complexities that now-smaller staffs must manage.  Never has the need for comprehensive enterprise-wide information management and analysis been greater. A highly integrated Laboratory Information Management System (LIMS) can open the doors to new R&D investment.

Pharma QA/QC Labs Look to LIMS for GLP, SOPs and QbD

Pharma QA/QC Labs rely on LIMS for QbD

While the paperless laboratory has been a topic of discussion for some time, the pace of adoption has never been faster. And since the collaborative landscape has changed dramatically in the past several years and increased the speed of discovery, alliances between commercial, academic and private research have become more complex.  These new layers of collaboration now require a different kind of integration of not just partners, but of inter-connected systems used by all of these collaborators. 

Too Much Data on your Plate? LIMS to the Rescue.

Too Much Data on your Plate? LIMS to the Rescue.

The food supply chain has become a complex global system consisting of small to large domestic and foreign manufacturers, processors, packers, distributors and transporters with few common business practices. Consumers now expect year-round supplies of fresh fruits and vegetables as well as more the more exotic, including processed  foods. This has increased the risk of a major food safety incident. Compliance with differing government regulations and enforcement policies adds to the complexity. With such a wide-spread value chain with multifaceted reporting requirements, the challenges are great for consumer-facing suppliers to demonstrate regulatory compliance and protect their brands. Laboratory information management systems (LIMS) play a key role in brand protection by facilitating end-to-end traceability of products and all associated laboratory processes.

BioFuels Production: Driven by LIMS

C  Users patricia.mcdermott Pictures sugar cane 1 resized 600

A laboratory information management system (LIMS) is one of the most critical components of any laboratory in a modern oil and gas company – managing data and automating laboratory processes from the exploration and extraction stages to the production and refining parts of the business.  And now with a focus on alternative methods of recovering oil and gas, from hydraulic fracturing (or fracking) to deep water drilling, the data related to every stage of production must be securely captured, stored and made available to any number of constituents who may need it – from on-site managers determining the quality of output, downstream production or manufacturing who may be taking customer orders and establishing workflow for ongoing projects, to management who may need to report on plant efficiencies and cost savings or compliance to shareholders or regulatory bodies.  A LIMS is the critical data and lab management tool that allows the lab to run as efficiently as possible, with instruments and equipment integrated with the LIMS and the LIMS fully integrated with other enterprise systems, such as PIMS, MES or ERP.  Such a tightly integrated laboratory also relies on a method or  lab execution system (LES) to enable the most efficient automated workflow, where lab personnel are given precise instructions on fast-changing sampling requirements or project turn-over, instruments are monitored for timely recalibration and maintenance, and  personnel training records are part of the permission process for access to instruments required for certain critical procedures. 

Question for LIMS Users: Are You Optimizing Your Investment?

lab informatics systems

Remind yourself what that laboratory software is there to do - and attend a complimentary one-day event with industry professionals in the UK, London, Thursday May 1.

Take Control of Your Lab Workflow with SampleManager LIMS

C  Users patricia.mcdermott Pictures Lab Execution Image HI RES resized 600

Exciting things are happening at Thermo Fisher Scientific, and I wanted to keep you informed of our latest developments. We’ve just come back from Smart Lab in Germany and Pittcon in Chicago - and are preparing for a full show season – Arab Lab is next week, and Analytica, the largest of the European events, will take place first of April. What are we excited about?   We’ve just launched our Lab Execution System (LES), the newest set of functionality for SampleManager LIMS.  Now SampleManager LIMS offers instrument integration capabilities through our Integration Manager, raw data storage and retrieval through our SDMS capabilities as well as the new LES functionality, making SampleManager LIMS the most comprehensive paperless lab solution available today.  SampleManager is currently the only Informatics solution to combine LIMS, LES and SDMS functionality on one enterprise-level platform.  The new LES is web-based, built on and fully integrated with the Thermo Scientific enterprise-level LIMS platform, allowing the LES functionality to be executed from the LIMS or from any web browser. I’ve got a short video  for you to watch, featuring Trish Meek, from Thermo Fisher. She took the time on the floor of Pittcon to talk about some of the key features of the new Lab Execution System and why this functionality brings our paperless lab offering full circle for our customers. 

LIMS Delivers Lab Data that can Transform a Business

comp data collage

There’s a lot of conversation these days about data, where it comes from, who needs it and how to manage it. For industries in all market segments, data is being generated at such a pace that it requires new thinking in terms of how that data is captured and managed.  For companies that rely on laboratory data as a key contributor to their business metrics, the issue is compounded by regulatory concerns, the need for more collaboration and data sharing with multiple parties and, in some cases, privacy concerns where individual or patient information is captured.  For all of these businesses, a laboratory data management system (LIMS) is an essential component of a sophisticated laboratory environment, enabling the lab to fully integrate all of its instrumentation and equipment, and by further integrating the laboratory with existing enterprise systems, enabling the use of lab data as a key business metric delivered to management.  Companies that fully explore and invest in enterprise integration strategies have more opportunity to capitalize on new growth opportunities and give themselves the agility to take active steps to transform the business as management requires.

LIMS Webinar - Lean Lab Informatics and the Paperless Lab

A LIMS Solution for Pharma Manufacturing

Many organizations have made significant investments in enterprise and laboratory tools, technologies and solutions to improve productivity, better manage data and optimize their business processes.  ERP systems are used for enterprise connectivity, PIMS and MES are implemented at the manufacturing level and LIMS, CDS, ELN and SDMS are in place to support the laboratory environment.   While these solutions are designed to optimize each specific area of operation, they are not often integrated with each other. The result is that these solutions become data islands that are accessed by different users, with little connectivity to enable a smooth flow of information across the enterprise. This lack of connectivity is one of the key reasons many companies do not realize a full return on investment (ROI) or the efficiency gains they had planned.

LIMS and the Paperless Lab - An Introduction to Integration Manager

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There’s no question that one of the key drivers in lab-centric businesses today is connectivity – integrating all of the disparate instruments in the laboratory, such as chromatography and mass spec,  with data management systems like LIMS (laboratory information management system) or CDS (chromatography data system). What’s needed further is complete integration of these laboratory sources of data with enterprise systems such as ERP, PIMS or MES.  This type of integration now makes data available across the organization to anyone needing it, in real time, and this greatly enhances the ability of management at any level to make knowledgeable decisions that achieve key business metrics.

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