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A blog on the latest applications, articles, & research on chromatography solutions in sample preparation, Ion Chromatography (IC),
High Pressure Liquid Chromatography (HPLC), Ion Chromatography-Mass Spectrometry (IC-MS), Gas Chromatography (GC),
Gas Chromatography-Mass Spectrometry (GC-MS and GC-MS/MS), and software (Chromeleon CDS, LIMS, and ProteinCenter).

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Speeding Universal Method Transfer from HPLC to UHPLC!

  
  
  
  
  
  
hplc method transfer to uhplc

Can you easily and quickly apply all rules for a successful HPLC-to-UHPLC method transfer? If you are doing this frequently, you are probably doing the math on a piece of paper each time and wasting valuable time; here, we are pleased to present a tool plus a technical note that could help speed things up significantly for chromatographers!

HPLC Enhancements for Fast Biopharma Analysis: On-Demand Webinar

  
  
  
  
  
  
charge variant and glycan analysis

The on-demand webinar (under 60 mins) featured in this post was recently posted on our website and you can view it without filling out a registration form! The webinar presents our new Bio-UHPLC platform (Thermo Scientific Dionex UltiMate 3000 BioRS system) and consumables for charge variant and glycan analysis.

LC-MS Analysis of Degradation Products of V Nerve Agents!

  
  
  
  
  
  
trace analysis of nerve gas degradation products

We have very small toxicology and forensic application sections on this blog but ever since I wrote about the use of our LC-MS systems in a UK study on suspected chemical warfare used by the Russian Special Forces during the course of the Moscow Theater Siege in 2002 (link to post), I have been fascinated by the subject. Hence, when I recently received notification about another similar study, again using one of our LC-MS solutions, for the study of degradation products of nerve agents, it was on the top of my list to write about.

Chromatography Monitoring as per U.S. EPA UCMR 3: Two Webinars

  
  
  
  
  
  
UCMR 3 inorganic and organic contaminant analysis

The two-parts of this upcoming webinar series presented in this post cover multiple chromatography techniques (gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, ion chromatography, and Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry) for the monitoring of inorganic and organic contaminants as per the U.S. EPA's Unregulated Contaminant Monitoring Rule 3 (UCMR 3) (link to U.S. EPA page). Both webinars will feature a customer case study from Eurofins Eaton Analytical Inc.; Dr. Andy Eaton, Vice President and Technical Director at Eurofins Inc. will be in a discussion with Dr. Richard F. Jack, our NA Environmental Market Manager at Thermo Fisher Scientific Inc.

Chromatography Data System: Five Webinars to Speed up your Analysis!

  
  
  
  
  
  
chromatography software

I am pleased to present a series of five upcoming webinars on features in our using our award-winning chromatography data system (CDS) software (Thermo Scientific Dionex Chromeleon CDS software)! The goal of the webinars is to present the CDS software features that permit chromatographers to get the analysis right first time!

Chromatography Solution Online Center Now Open!

  
  
  
  
  
  
liquid chromatography, ion chromatography, gas chromatography, and chromatography software

Do you know about our collaboration with Chromatographyonline.com in presenting an online Chromatography Solution Center to serve as a resource for chemists, scientists, and researchers by presenting the latest developments and applications, in chromatography?

LC-MS/MS Study of Metabolomic Changes in Nematode C. elegans

  
  
  
  
  
  
metabolomic analysis

I found the HPLC and mass spectrometry metabolomics application blogged here fascinating as I had just read about the destructive impact of nematodes on food crops (link to story), and after receiving the application note, I was compelled to do some research on the Internet on the particular nematode studied in the application, namely Caenorhabditis elegans. (Isn't the image accompanying this post beautiful?)

Ion Chromatography Environmental Microbiology Research Studies (3)

  
  
  
  
  
  
bacteria studies using ion chromatography

After two earlier posts on the use of ion chromatography in microbiology research studies in the environment, I am pleased to present five more research studies on the topic. (The previous posts are Ion Chromatography Environmental Microbiology Water Studies (I) and Ion Chromatography Microbiology Research Studies (2)).

Chromatography Software Provides Third-Party Instrument Control!

  
  
  
  
  
  
chromatography instrument control software

I am pleased to feature a recently released white paper describing the evolution of the third-party instrument control feature in our award-winning Chromatography Data System (CDS) software (Thermo Scientific Dionex Chromeleon CDS software) with a printer driver plugin and a Driver Development Kit (DDK).

LC-MS Workflow Speeds Analysis of Monoclonal Antibody Drug Rituximab

  
  
  
  
  
  
analysis of monoclonal antibodies

When I received notice about the application note blogged here, I realized it has been a while since I have written about the analysis of monoclonal antibodies (MAbs) using our systems! Here, I am pleased to present a method that was developed as a collaboration between our chemists and researchers from the University of Salzurg (Austria). The method features an optimized and fast HPLC and mass spectrometry workflow for the analysis of Rituximab, a first new-generation drug approved to treat lymphomas, leukemia, transplant rejection, and autoimmune disorders. (Source & link Wikipedia)

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