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A blog on the latest applications, articles, & research on chromatography solutions in sample preparation, Ion Chromatography (IC),
High Pressure Liquid Chromatography (HPLC), Ion Chromatography-Mass Spectrometry (IC-MS), Gas Chromatography (GC),
Gas Chromatography-Mass Spectrometry (GC-MS and GC-MS/MS), and software (Chromeleon CDS, LIMS, and ProteinCenter).

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Chromatography Analysis of Sugars & Sweeteners in Beverages (I)

chromatography sugars in beverages

Have you been following the increasing efforts by various governments to regulate the amount of sugar in beverages or impose sugar taxes on sugary drinks in an effort to reduce sugar in food and beverage products? In one story, UK's chief medical officer told a committee of MPs that a sugar tax may have to be introduced to curb obesity rates (link to story) and in another story, the state of Illinois, in the USA, is considering a new tax on sugary beverages (link to story). By the way, a new study concluded that fruit juice has only a bit less fructose than sugary sodas (link to study).

Why Settle for Cr(VI) 20 ppt When You Can Get 1 ppt in Half the Time?

hexavalent chromium testing

I know the title does not sound as one of our typical titles but I thought I would focus on the test results rather than the technology for once. By the way, did you know that it has already been more than two years ago since we first alerted you on new detection limits for hexavalent chromium (the topic is the subject of the blog post: Ion Chromatography Analysis of Hexavalent Chromium) and how the U.S. EPA has used our ion chromatography technology to develop the U.S. EPA Method 218.6 way back in 1991 for the determination of Cr(VI) in drinking water.

HPLC Solid-Core Columns For Fast Pharma Analysis (II)

HPLC analysis of Analgesic Compounds

In Part II on our solid-core HPLC columns, I am pleased to feature two application notes featuring the use of these columns in pharma and biopharma development. (Part I, HPLC Solid-Core Columns For Fast Pharma Analysis (I), featured a technical article, a technical note, and an on-demand webinar.)

GC-MS & GC-ECD Methods for Pesticides in Fruit & Tea Research Studies

gc-ecd pesticides in tea

Here, I am pleased to present two research studies describing the use of gas chromatography-mass spectrometery (GC-MS) and gas chromatography-electro capture dectectorchemical (GC-ECD) for the analysis of pesticides in strawberries and tea respectively. Sounds like a lovely English afternoon doesn't it except for the pesticides bit. Did you know that 80% of the strawberries in the United States are supplied by one state, that is, California? Here's a comprehensive read on all you ever wanted to know about strawberries from how they are grown, why are they getting bigger and yet less flavorful, and what organic strawberries actually mean: The Secret Life Of California's World-Class Strawberries (link to article).

Ion Chromatography Method for Analysis of Denatured Ethanol

analysis of sulfate and chloride in denatured ethanol

This post features an updated ion chromatography method for the analysis of sulfate and chloride in denatured ethanol in which it is not required to prepare sulfuric acid for electrolytic suppression. (Previously, this blog post, Ion Chromatography Analysis of Denatured Fuel Ethanol Samples, described a direct injection method for determining chloride and sulfate in fuel ethanol as per ASTM D-7319.)

Sample Preparation for Analytes Susceptible to Degradation or Loss

bioanlysis sample preparation

Here is the third application note in this series on improving sample preparation for bioanalytical and clinical research applications using our recently released solid-phase extraction (SPE) micro elution plates (Thermo Scientific SOLA┬Á Solid Phase Extraction [SPE] Well Plates). The previous two application notes are presented in the following blog posts:

Too Much Data on your Plate? LIMS to the Rescue.

Too Much Data on your Plate? LIMS to the Rescue.

The food supply chain has become a complex global system consisting of small to large domestic and foreign manufacturers, processors, packers, distributors and transporters with few common business practices. Consumers now expect year-round supplies of fresh fruits and vegetables as well as more the more exotic, including processed  foods. This has increased the risk of a major food safety incident. Compliance with differing government regulations and enforcement policies adds to the complexity. With such a wide-spread value chain with multifaceted reporting requirements, the challenges are great for consumer-facing suppliers to demonstrate regulatory compliance and protect their brands. Laboratory information management systems (LIMS) play a key role in brand protection by facilitating end-to-end traceability of products and all associated laboratory processes.

Capillary Ion Chromatography & HR/AM: Metabolite Profiling of Cancer

chromatography analysis of cancer polar metabolites

Did you know that metabolomics (systematic study of the unique chemical fingerprints that specific cellular processes leave behind) is increasingly used in the study of oral cancers? (Definition: Wikipedia)

Gas Chromatography Speeds Analysis of Petroleum (III)

Analysis of Petroleum Products

Part III on this series on chromatography applications for the analysis of oil and gas refinery products features some of our gas chromatography resources. (Part I in this series is featured here: Ion Chromatography Speeds Petroleum Refinery Analysis (I) and Part II is featured here: LC-MS Platform for the Analysis of Finished Petroleum Products (II))

Chromatography Solutions for Analysis of Milk

hplc milk analysis
How this blog post on the chromatography analysis of milk and milk products came about was the featuring of the following two fascinating stories on our twitter stream and our Chromatography Solutions Facebook page on the topic:
  • Did you know that before refrigeration, people in Russia and Finland dropped live brown frogs into milk to keep it fresh? Moscow State University researchers discovered the science behind this odd custom; they found that amphibians' skin secretions are filled with peptides, which are antimicrobial compounds that are as effective against Salmonella and Staphylococcus bacteria as prescription antibiotics. 
  • The ability of geographically diverse Africans to digest milk has been linked to spread of cattle raising. Researchers found that the ability to digest milk became a selective force in the populations that raised cattle and consumed fresh cow, camel, or goat milk and identified three additional genetic variants with lactase persistence that had not been identified previously. By the way, it was the largest ever study of its kind in Africa.

In our 90-plus page Beverages Applications Notebook: Milk (downloadable PDF), we present applications for monitoring the compositional quality and safety of milk and milk products such as baby formula, lactose-free milk products, and milk for tracking contamination, adulteration, product consistency, and to ensure regulatory compliance.

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