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A blog on the latest applications, articles, & research on chromatography solutions in sample preparation, Ion Chromatography (IC),
High Pressure Liquid Chromatography (HPLC), Ion Chromatography-Mass Spectrometry (IC-MS), Gas Chromatography (GC),
Gas Chromatography-Mass Spectrometry (GC-MS and GC-MS/MS), and software (Chromeleon CDS, LIMS, and ProteinCenter).

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GC-MS & GC-ECD Methods for Pesticides in Fruit & Tea Research Studies

gc-ecd pesticides in tea

Here, I am pleased to present two research studies describing the use of gas chromatography-mass spectrometery (GC-MS) and gas chromatography-electro capture dectectorchemical (GC-ECD) for the analysis of pesticides in strawberries and tea respectively. Sounds like a lovely English afternoon doesn't it except for the pesticides bit. Did you know that 80% of the strawberries in the United States are supplied by one state, that is, California? Here's a comprehensive read on all you ever wanted to know about strawberries from how they are grown, why are they getting bigger and yet less flavorful, and what organic strawberries actually mean: The Secret Life Of California's World-Class Strawberries (link to article).

Ion Chromatography Method for Analysis of Denatured Ethanol

analysis of sulfate and chloride in denatured ethanol

This post features an updated ion chromatography method for the analysis of sulfate and chloride in denatured ethanol in which it is not required to prepare sulfuric acid for electrolytic suppression. (Previously, this blog post, Ion Chromatography Analysis of Denatured Fuel Ethanol Samples, described a direct injection method for determining chloride and sulfate in fuel ethanol as per ASTM D-7319.)

Sample Preparation for Analytes Susceptible to Degradation or Loss

bioanlysis sample preparation

Here is the third application note in this series on improving sample preparation for bioanalytical and clinical research applications using our recently released solid-phase extraction (SPE) micro elution plates (Thermo Scientific SOLAµ Solid Phase Extraction [SPE] Well Plates). The previous two application notes are presented in the following blog posts:

Too Much Data on your Plate? LIMS to the Rescue.

Too Much Data on your Plate? LIMS to the Rescue.

The food supply chain has become a complex global system consisting of small to large domestic and foreign manufacturers, processors, packers, distributors and transporters with few common business practices. Consumers now expect year-round supplies of fresh fruits and vegetables as well as more the more exotic, including processed  foods. This has increased the risk of a major food safety incident. Compliance with differing government regulations and enforcement policies adds to the complexity. With such a wide-spread value chain with multifaceted reporting requirements, the challenges are great for consumer-facing suppliers to demonstrate regulatory compliance and protect their brands. Laboratory information management systems (LIMS) play a key role in brand protection by facilitating end-to-end traceability of products and all associated laboratory processes.

Capillary Ion Chromatography & HR/AM: Metabolite Profiling of Cancer

chromatography analysis of cancer polar metabolites

Did you know that metabolomics (systematic study of the unique chemical fingerprints that specific cellular processes leave behind) is increasingly used in the study of oral cancers? (Definition: Wikipedia)

Gas Chromatography Speeds Analysis of Petroleum (III)

Analysis of Petroleum Products

Part III on this series on chromatography applications for the analysis of oil and gas refinery products features some of our gas chromatography resources. (Part I in this series is featured here: Ion Chromatography Speeds Petroleum Refinery Analysis (I) and Part II is featured here: LC-MS Platform for the Analysis of Finished Petroleum Products (II))

Chromatography Solutions for Analysis of Milk

hplc milk analysis
How this blog post on the chromatography analysis of milk and milk products came about was the featuring of the following two fascinating stories on our twitter stream and our Chromatography Solutions Facebook page on the topic:
  • Did you know that before refrigeration, people in Russia and Finland dropped live brown frogs into milk to keep it fresh? Moscow State University researchers discovered the science behind this odd custom; they found that amphibians' skin secretions are filled with peptides, which are antimicrobial compounds that are as effective against Salmonella and Staphylococcus bacteria as prescription antibiotics. 
  • The ability of geographically diverse Africans to digest milk has been linked to spread of cattle raising. Researchers found that the ability to digest milk became a selective force in the populations that raised cattle and consumed fresh cow, camel, or goat milk and identified three additional genetic variants with lactase persistence that had not been identified previously. By the way, it was the largest ever study of its kind in Africa.

In our 90-plus page Beverages Applications Notebook: Milk (downloadable PDF), we present applications for monitoring the compositional quality and safety of milk and milk products such as baby formula, lactose-free milk products, and milk for tracking contamination, adulteration, product consistency, and to ensure regulatory compliance.

HPLC Solid-Core Columns For Fast Pharma Analysis (I)

hplc pharma analysis columns

A two-part series on several resources for our solid-core HPLC columns has been on my to-do list for a while now and kept getting pushed back down the list every week until I decided that I simply had to write about them. So, here goes.

GC-MS & LC-MS Methods for Analysis of Pesticide Poisoning in Wildlife

gc-ms analysis of wildlife poisoning

Did you know that poisons, and pesticides in particular, have been used to kill wildlife all over the world and now 83% of African countries have banned the killing of wildlife with poisons? (Link to study.) I learned that wildlife is poisoned as some animals are considered a nuisance for humans while other animals, birds, and fish are poisoned as they are used as sources of food, traditional medicines, or products. In the study linked to in the first sentence, Dr. Ogada of The Peregrine Fund (National Museums fo Kenya, Kenya), calls for "banning pesticides, improving pesticide regulations and controlling distribution, better enforcement and stiffer penalties for offenders, increasing international support and awareness, and developing regional pesticide centers."

LC-MS Platform for the Analysis of Finished Petroleum Products (II)

chemical characterization of petroleum

In Part II of this series on chromatography solutions for the analysis of oil and gas refinery products, I am pleased to present a robust LC-MS method for the complete analysis of finished petroleum products. (Part I is featured here: Ion Chromatography Speeds Petroleum Refinery Analysis (I).)

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