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A blog on the latest applications, articles, & research on chromatography solutions in sample preparation, Ion Chromatography (IC),
High Pressure Liquid Chromatography (HPLC), Ion Chromatography-Mass Spectrometry (IC-MS), Gas Chromatography (GC),
Gas Chromatography-Mass Spectrometry (GC-MS and GC-MS/MS), and software (Chromeleon CDS, LIMS, and ProteinCenter).

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HPAE-PAD Analysis of Uronic Acids in Biofuel Biomass

  
  
  
  
  
  
analysis of Uronic Acids in Biomass

Did you know that the leaders in production of biofuels are the United States, France, Sweden, and Germany? And, the goal in the U.S. is to replace 75% of its imported oil by 2025 by alternative power sources including biofuels? (Source & Link Wikipedia).

HPLC Measurement of Copper Additives in Electroplating Baths

  
  
  
  
  
  
Copper Additives in Electroplating Baths

I know the HPLC analysis of plating baths for electronics may not sound exciting but I found the white paper featured here on this subject to be fascinating reading. And, it led me to doing a little research. Did you know that damascene, or acid copper plating baths, have been in use since the mid 19th century on decorative items and machinery, including integrated circuits and satellites in recent times? And, that the art of inlaying different metals into one another is called damascening, from the resemblance of such items to patterns of damask silk (link & source Wikipedia)? 

HPLC Simplifies Analysis of Artificial Sweetner Acesulfame in Vinegar

  
  
  
  
  
  
analysis of acesulfame potassium by hplc

I found the HPLC application, briefly discussed in this blog post, for the analysis of a synthetic sweetener called Acesulfame or Acesulfame K in vinegar fascinating as I had no idea that it is extensively used as a sugar substitute in foods and beverages. Some food regulatory bodies, such as The Standardization Administration of China allows Acesulfame to be added to fermented vinegar products, but limits the added amount to no more than 4 µg/mL. Therefore, an efficient method is needed to sensitively and rapidly determine Acesulfame in fermented vinegar. By the way, Acesulfame is 200 times sweeter than sucrose.

GC-MS Rapid and Reliable Detection of Dissolved Gases in Water

  
  
  
  
  
  
gc analysis of fracking gases

I am pleased to present a recently developed, simple, reliable and robust gas chromatography method for identifying and quantifying methane, ethane, ethylene, and propane in environmental waters affected by hydraulic fracturing operations. (In case you are interested in this subject, the last post on this topic was in September and was titled, Ion Chromatography Speeds Hydraulic Fracturing Wastewater Analysis.)

Ion Chromatography Improves Analysis of Airborne Particulate Matter

  
  
  
  
  
  
analysis of small particles in the air

On receiving notification on the release of an ion chromatography application for the analysis of airborne particulate matter, I realized the last application on this subject was more than six months ago! This new method determines more analytes relevant to air contamination (link to U.S. EPA page on air pollutants) than either of the two standard methods currently in use.

Monoclonal Antibody High-Resolution Separations Using HIC

  
  
  
  
  
  
hic analysis of monoclonal antibodies

A few weeks ago, I featured a method for the analysis of monoclonal antibodies (MAbs) on a recently released hydrophobic interaction chromatography (HIC) column (link to post) and, here, I am pleased to feature another method on another newly released HIC column (Thermo Scientific MAbPac HIC-10 column)! This new column is a high-resolution, silica-based HIC column designed for separation of mAbs and variants, including anti-body conjugates (ADCs) and provides high resolution, excellent bio-compatibility, and selectivity as compared to HIC columns on the market.

Ion Chromatography Provides Direct Analysis of Diesel & Biodiesels

  
  
  
  
  
  
analysis of sodium in diesel biodiesel (2)

It has been a long time since I written about chromatography applications for biofuels, and here I am pleased to present, no less, a customer application that includes an automated in-line matrix removal technique for the direct trace determination of sodium in nonwater miscible liquids, such as, diesel, biodiesel, and other fuels! Interestingly, the sources for the sodium contamination in fuel include remaining catalyst from biodiesel fuel production, drying agents, corrosion inhibitors, sea water from tanks (i.e., ballast water), and sodium components from pipelines.

Gas Chromatography Analysis of Methane & Carbon Dioxide in Beer Waste

  
  
  
  
  
  
analysis of spent brewers grain

Did you know that the world beer consumption was 187.37 million kiloliters in 2012  and China remains the largest beer-consuming country for the 10th year running? (Source and link to Kirin Beer University Report.) The challenge remains of dealing the spent brewer's grain used to produce beer, and typically, over 300,000 tonnes of this spent grain is produced annually. While it is used successfully as an animal feedstock, the spent grain deteriorates rapidly due to its high humidly and fermenting sugar content. In the gas chromatography research study, presented in this post, researchers present novel methods for drying the spent grain by using the bio-energy generated from the anaerobic digestion of the spent grain in the same brewery!

HPAE-PAD Speeds Analysis of Carbohydrates in Beverages & Milk

  
  
  
  
  
  
analysis of carbohydrates in apple cider

The ongoing challenge for food regulatory bodies is not just identifying food contamination problems but also making sure that product formulation and product quality meets regulatory standards and food manufacturers report any ingredients that might impact immune-and allergy-sensitive individuals. By the way, did you know that India has banned the import of milk and milk products from China until June 2015 due to concerns of contamination of melamine? And. you can read about our solutions on the analysis of melamine in pet food and milk (link to post) on this blog.

HPLC Toxiology Research Articles on Analysis of Illicit Drugs

  
  
  
  
  
  
hplc toxicology analysis

I have mentioned before on this blog that I am fascinated by the subject of toxicology and find peer-reviewed articles featuring the use of chromatography, such as the two articles featured here, absolutely riveting. By the way, did you know that the pace at which new and illicit psychoactive substances have been emerged has speeded up tremendously in the last few years?

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