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A blog on the latest applications, articles, & research on chromatography solutions in sample preparation, Ion Chromatography (IC),
High Pressure Liquid Chromatography (HPLC), Ion Chromatography-Mass Spectrometry (IC-MS), Gas Chromatography (GC),
Gas Chromatography-Mass Spectrometry (GC-MS and GC-MS/MS), and software (Chromeleon CDS, LIMS, and ProteinCenter).

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UHPLC-MS Analysis of Psychotropics in Mushrooms and Chocolate

  
  
  
  
  
  
Psychotropics in Mushrooms and Chocolate

I found this fascinating application, featured here, presenting an UHPLC-MS method for the analysis of the psychotropic substances psilocybin and psilocin in mushrooms and chocolate on our website while looking for information on one of our UHPLC systems and thought it would make a great read on this blog! The method was developed by our chemists at our San Jose lab (California, USA) in collaboration with the Crime Laboratory of the Washington State Patrol (Washington, USA) to aid in the identification of controlled substances, such as psychotropics, in small quantities of seized evidence.

HPLC Solution Kit for Simultaneous Analysis of Pharma Counterions

  
  
  
  
  
  
hplc counterion analysis

I am pleased to present our recently released HPLC counterion solution kit for pharmaceutical QA/QC (Thermo Scientific IonCount solution) which simplifies the analysis and setup of complete HPLC workflows for common and less common organic and inorganic counterions in pharmaceutical analysis. Those working in this field know that obtaining qualitative and quantitative information of pharmaceutical drugs and residual salts is critical for determining the purity, mass balance and stoichiometry of drug formulations and this solution can speed up the screening and assaying of a broad variety of counterions and active pharmaceutical ingredients (APIs).

Chromatography and Sample Preparation Terminology Guide

  
  
  
  
  
  
chromatography terminology

In this very short blog post, I wanted to provide a link to a great resource, Advanstar Science's Chromatography and Sample Preparation Terminology Guide (link to page where you can click Register, fill out a brief form and then download the guide).

Accelerated Solvent Extraction: Fast Extraction of Fat in Snack Foods

  
  
  
  
  
  
fat determination in snacks

Reading this application update on a faster sample preparation method for the extracting total unbound fat from packaged foods, I learned that many regulatory agencies, such as the US FDA, the Food Safety and Standards Authority of India, UK's Dept for Environment, Food & Rural Affairs, and the Australia New Zealand Food Standards Code, require that the nutritional content including fat in processed and packaged food is declared on the product label. (Links open labeling regulatory pages or PDFs.)

Ion Chromatography: Municipal Water Analysis Applications Notebook

  
  
  
  
  
  
Municipal Water Analysis Applications

Did you know that the state of California in the USA is heading into year three of its worst drought of 40 years? (Link to story.) Experts in the state are looking at efficiencies and reuse of water sources, such as agricultural and urban water, water reuse and recycling, and increased capturing of local rainwater.

Ion Chromatography Analysis of Impurities in Drug Lithium Carbonate

  
  
  
  
  
  
lithium carbonate analysis

Here, I am pleased to present a recently developed fast ion chromatography method for the  simultaneous determination of lithium, sodium, and calcium in the drug lithium carbonate (link to U.S. National Library of Medicine) without the handling hazardous reagents.

HPLC Method for Metabolite Profiling of Wine, Juice, & Tea

  
  
  
  
  
  
metabolite profiling of tea wine fruit juice

I am pleased to present a recently released application note featuring a gradient HPLC method to study product authenticity, such as differentiating wine varietals, orange juice varietals and growing region, and distinguishing tea blends, and identifying adulteration in juices, such the blending of orange juice with cheaper juices or the inclusion of peel or pulp wash.

HPLC & CAD: Surfactants and Emulsifiers Applications Notebook

  
  
  
  
  
  
analysis of emulsifiers and surfactants using hplc

Did you know that the global food emulsifiers market is one of the fastest growing markets in the food ingredient market and is estimated to grow to $2,858.6 million by 2018? (Link to market research website.) Emulsifiers are used to stabilize emulsions in the food industry plus used as an additive to reduce fat content. Surfactants are compounds that lower the surface tension between liquids or a liquid and a solid, and are used as detergents, wetting agents, emulsifiers, foaming agents, and dispersants. (Definition and link Wikipedia page.) Other important uses of surfactants include industrial applications in lubrication, textile processing, petroleum recovery, and wastewater treatment.

GC-MS Analysis of Pesticides: Downloadable e-Book!

  
  
  
  
  
  
analysis of pesticide residues GC–MS

I am so pleased to offer you this new 52-page interactive e-book, developed by LCGC, on the advances in the analysis of pesticide residues using gas chromatography–mass spectrometry (GC–MS) methods.

HPLC Applications Notebook: Traditional Chinese Medicine

  
  
  
  
  
  
Traditional Chinese Medicine HPLC analysis

Did you know that the oldest work on Traditional Chinese Medicine (TCM) appeared in 200 B.C. and that the first TCMs and acupuncture needles appeared around 2500 BCE in China? (Link to site.) And, here I am pleased to present to you our recently released notebook featuring HPLC applications for TCM to help ensure the efficacy, purity and safety of these traditional remedies!

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